Gilligan's Island has gone from uncharted territory to biologists' paradise. Read more to find out what makes being a laboratory manager at the Hawaii Institute of Marine Biology on beautiful Coconut Island in Kaneohe Bay, Oahu such a cool job!

What is your job?

I am the manager of the Evolutionary Genetics Core Facility at the Hawaii Institute of Marine Biology (HIMB), located on the beautiful Coconut Island in Kaneohe Bay, Oahu. The purpose of this facility is to provide technical services and support for researchers at HIMB, the University of Hawaii system, as well as other institutions worldwide (such as NOAA and the USDA). The scientific instruments and equipment contained at the Core facility are available for general use of researchers, and includes: a Microarray to measure gene expression levels, a Spectrophotometer to measure DNA, RNA and proteins, and real time PCR instrument to quantify DNA. I am available on site to offer assistance with instrument protocols and troubleshooting.

The facility also offers genomic services including Sanger and Illumina sequencing and fragment analysis. (DNA Sequencing determines the order of nucleotides in DNA molecule, and fragment analysis identifies DNA fragments based on size.) These services can be used for various applications such as genome sequencing, mutation detection, gene identification and expression, and genotyping.

While I work at a marine institute, I am not a marine biologist. My degree is in biology, and my work experience and expertise is in molecular biology, which is the study of biology at the molecular level.

Why did you choose this career?

I am a lab rat. I love working in the lab, learning new protocols or experiments, troubleshooting, and discovering how and why things work.

Explain what an average day at work is like for you.

There isn't one! For me, every day is different. One day I could be running experiments on coral gene expression or shark and dolphin genetics for researchers, and the next I could be discussing designs for research projects, or educating researchers about the technologies used in the facility. What I do each day depends on the needs of the people using the facility.

The only thing that doesn't change for me is my daily water commute. To access my lab I must go by boat, which runs from the main island of Oahu to the famous Coconut Island. Coconut Island is best known from its appearance during the opening credits of the 1960's TV show "Gilligan's Island"! I love the boat ride because I get to take in beautiful views of the Koolau mountains.

What do you like best about your job?

I get to contribute to many different research projects. Without the equipment, services, and support provided by my laboratory, many researchers wouldn't be able to conduct their experiments. The instrumentation and services offered by my laboratory are important tools for scientific research being conducted in Hawaii.

When you were a kid, did you like science, engineering and/or math? 

My favorite subject was math because I understood it and was good at it. Mathematics made more sense to me than other subjects.

Was there a moment when you knew you wanted to become a molecular biologist?

There wasn't a specific moment that I knew I wanted to become a scientist, but my interest in science started early. In sixth grade I got to dissect a cow eyeball in science class. We looked at all of the components of the eyeball, and studied their individual functions. I thought it was so cool that I decided to bring the eyeball home and save it in my refrigerator. That's when I also learned that my mother is a screamer!

Throughout middle school and high school I really enjoyed math and physics classes. In college I discovered that science classes were really my favorite, and once I got my first job in a laboratory, everything really fell into place. I was able to work at my own pace in a calm, quiet setting. I also discovered I was good at precision work, and I knew at that point that I had found where I belonged.

What was the biggest challenge you faced on your journey to becoming a scientist?

My biggest challenge was learning patience. Research can be a long process, and there are many small but important steps involved in reaching a goal. I had to learn that each step requires time, patience and accuracy. You have to work for your discoveries!

Was there a person who inspired or convinced you to get involved with your field? 

I was most inspired by my former neighbor, Tanya Vickers. Tanya taught biology at the University of Utah, and assisted me in getting my first lab job, as well as providing great encouragement and support. I am convinced that I wouldn't be where I am today without Tanya's guidance.

Do you have any suggestions for how undergraduate students can get practical experience in your field?

Volunteer your time in the laboratory or in the field. Also, contact the professors who are conducting research at your school, as most professors will be happy to receive some extra help. As a volunteer you will gain hands-on experience in the research process. If there are no volunteer opportunities available, try explaining to the researcher that you are interested in their project and ask if you can shadow them.

What post-graduate opportunities exist for students?

There are many careers to choose from in the field of biology. Some of the industries employing biologists include: environmental, medical, pharmaceutical, education, or clinical research. Take as many classes as you can to determine which industry appeals most to you.

Are there exciting things happening in your field that could involve students who will enter the field in 5 years?

For the first 3 years that I worked at HIMB, they solely offered Sanger sequencing and fragment analysis services. When HIMB first acquired an Illumina next generation sequencer, we were able to generate more sequencing data in 2 weeks than we had in the previous three years combined!

The cost to analyze and manage sequencing data is now greater than the cost to generate it. Scientists are overwhelmed with the amount of data that is generated, and new techniques are constantly being developed to analyze this data in the field of bioinformatics. This will be a key field in the future of science.

Bio Basics

• The human genome has over 3 billion base pairs, which is almost 10 times as many people living in the U.S. today
  
• The invertebrate animal group includes 97% of all animal species
• Human are not as different as we like to think.  Over 99% of our DNA sequence is the same as other humans' - less that 1% of our DNA determines inherited traits like eye and hair color. 

Key Terms

Bioinformatics: the retrieval and analysis of biochemical and biological data using mathematics and computer science, as in the study of genomes.

Gene Expression: Gene expression is the process of taking information from a gene into messenger RNA, and then to a protein.

Genome: Every organism has a genome. It is the material required to create a full set of chromosomes; all the inheritable traits of an organism.

NOAA: National Oceanic and Atmospheric Administration

USDA: United States Department of Agriculture